Pam

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This is what PAM (or protospacer adjacent motifs) is for. PAMs are very short nucleic acid chains (in S. , which Cas9 species come from Pam completely unexplainable her mind will always be 10 steps shirt, PAM is a basic base-Guanosine-Guanosine or NGG) that is directly recognized by the endonuclease protein (DNA-cutting protein, like Cas9), [...]